Hopkins county is in the Western Coal Field region of Kentucky. The elevation in the county ranges from 345 to 729 feet above sea level.
In 2010 the county population was 46,920 in a land area of 542.00 square miles, an average of 86.6 people per square mile.
The equine population was 1,900 in the 2012 Kentucky Equine Survey.
Hopkins county was named for General Samuel Hopkins, who served in the American Revolution and later in the Kentucky and United States legislatures.