Menifee county is in the Eastern Coal Field region of Kentucky. The elevation in the county ranges from 670 to 1428 feet above sea level.
In 2010 the county population was 6,306 in a land area of 203.59 square miles, an average of 31.0 people per square mile.
The equine population was 900 in the 2012 Kentucky Equine Survey.
Menifee county was named for Richard Hickman Menefee, who had been a congressman from the area. (The change in spelling was apparently the result of an error.)
Much of Menifee county is within the Daniel Boone National Forest, including part of Cave Run Lake.