Ohio county is in the Western Coal Field region of Kentucky. The elevation in the county ranges from 365 to 800 feet above sea level.
In 2020 the county population was 23,772 in a land area of 587.27 square miles, an average of 40.5 people per square mile.
The equine population was 1,000 in the 2012 Kentucky Equine Survey.
Ohio county is in the Green River Area Development District.
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