Scuffletown was a Henderson county community on the Ohio River about 12 miles northeast of Henderson. A river landing and tavern were established about 1800 and other commercial activity followed. The town was damaged by the 1913 flood and destroyed by the 1937 flood. The name is said to come from frequent fights at the tavern.
The Scuffletown post office opened in 1868 and closed in 1914.
The Newburgh Locks and Dam on the Ohio are located near the site of Scuffletown. The site of the old Ohio River Lock and Dam 47 was just downstream of the current Newburgh dam. The upstream dam 46 was at Owensboro and the downstream dam 48 was near Geneva.
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